Hysteroscopy with biopsy is a minimally invasive surgical procedure that allows a healthcare provider to examine the inside of the uterus using a hysteroscope—a thin, lighted tube with a camera. During this procedure, a tissue sample (biopsy) is obtained from the uterine lining for diagnostic purposes.

When it is Performed

Hysteroscopy with biopsy is performed when there is a need to investigate and diagnose various gynecological conditions and symptoms, such as abnormal uterine bleeding, irregular menstrual cycles, or suspected uterine abnormalities.

Purpose of the Procedure

The primary purposes of hysteroscopy with biopsy are:

Diagnostic Evaluation

To visually inspect the uterine cavity and obtain a tissue sample to diagnose conditions affecting the uterine lining.

Rule Out or Confirm Abnormalities

To determine the presence of uterine abnormalities, such as polyps, fibroids, endometrial hyperplasia, or cancer.

What is expected to be performed

Here is an overview of the procedure:


Hysteroscopy with biopsy can be performed under different types of anesthesia, including local anesthesia, regional anesthesia (spinal or epidural), or general anesthesia, depending on patient comfort and the provider's preference.

Insertion of Hysteroscope

The hysteroscope is inserted through the cervix into the uterus, allowing the provider to visualize the uterine cavity on a monitor.


Specialized instruments, such as biopsy forceps or curettes, are passed through the hysteroscope to obtain a small tissue sample from the uterine lining.

Tissue Collection

The tissue sample is collected and sent to a pathology laboratory for examination under a microscope.

End of Procedure

After the biopsy is obtained and the uterine cavity is examined, the hysteroscope is removed.


Hysteroscopy with biopsy typically involves no external incisions. The hysteroscope is inserted through the cervix, minimizing trauma to the surrounding tissues.

Surgical Instruments and Equipment

Surgical instruments used in this procedure may include the hysteroscope itself, biopsy forceps, or curettes for tissue collection.

Duration of Surgery

The duration of hysteroscopy with biopsy is relatively short, typically ranging from 15 to 30 minutes, although it may take longer if additional procedures are performed during the same session.

Intraoperative Monitoring

Standard monitoring equipment, such as vital sign monitors, may be used during the procedure to ensure the patient's safety.

Potential Complications

Potential complications of hysteroscopy with biopsy are generally rare but can include:

  • Uterine perforation (a small hole in the uterine wall).
  • Bleeding.
  • Infection.
  • Reaction to anesthesia.

Expected Outcomes

Hysteroscopy with biopsy helps healthcare providers diagnose conditions affecting the uterine lining accurately. The results of the biopsy can guide further treatment decisions.

– Alternatives to Surgery

Alternatives to hysteroscopy with biopsy may include transvaginal ultrasound or other imaging studies to evaluate the uterine cavity. However, hysteroscopy provides a more direct and detailed view of the uterine lining and allows for tissue sampling.

– Scarring

This procedure typically does not result in external scarring as it involves no external incisions.

Post-operative Care

Post-operative care may include:

  • Rest and recovery.
  • Monitoring for any unusual symptoms.
  • Follow-up appointments to discuss biopsy results and potential treatment options.

– Hospital Stay

Hysteroscopy with biopsy is often performed as an outpatient procedure, meaning that patients can usually return home on the same day without the need for a hospital stay.

Recovery Time

Recovery time is relatively short for hysteroscopy with biopsy. Patients may experience mild cramping and light bleeding for a few days after the procedure. Most individuals can return to their regular activities within a day or two, but it's essential to follow the post-operative care instructions provided by the healthcare provider.

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